Tirzepatide vs semaglutide cost in 2026

Both prices, from pages opened 26 October 2026

The comparison uses one published pair per commission-earning provider. The semaglutide figure and the tirzepatide figure have to come from pages opened that day, and they have to use the billing words the page prints. A 12-month per-month rate is not placed next to a month-to-month rate and called the same bill. A starting price stays a starting price.

The catalog already stores a continuing or prepaid figure for most of these rows. Where the page still prints that dollar, the table says so. Two readings differ from a single catalog number: Lttl had no stored price, and Embody's homepage cards do not match the one-month product pages. Those two are called out under the table.

Calendar-month pairs

yourEra is the low pair: $89 a month for semaglutide and $129 a month for tirzepatide, both month to month. The page says the 20% discount is auto-applied. The gap is $40. SnagRX's one-month columns are $99 and $149, a $50 gap. The 3-month, 6-month, and 12-month columns are lower on both drugs. The one-month column is the pair in this note. PlexusDx is $149 and $189 month to month, a $40 gap. The 12-month plans are $99 a month with $1,188 billed up front, and $129 a month with $1,548 billed up front. Those prepaid rates are real and they are not the month-to-month bill.

HealthRX is $99 due today, then $165 every month for semaglutide, and $99 due today, then $214 every month for tirzepatide. The later-month gap is $49. The pricing page says its prices are current as of October 15, 2026. The product pages opened 26 October still print these later-month dollars, which are the catalog figures checked 24 October 2026. Strut is $129 a month for the semaglutide injectable and $219 for the tirzepatide monthly vial, a $90 gap. Shed's 1-month plans are $199 and $299, a $100 gap. MEDGm is $179 then $299, and $279 then $399, so the later-month gap is $100. Willow is $299 and $399 a month, a $100 gap, and both pages were checked the same day the catalog stored those dollars.

A later-month price is the comparison figure when the page also prints a lower first charge. The first charge is a different bill.

Four-week bills and Found's 28-day cycle

Sprout Health's homepage bills compounded semaglutide at $149 every 4 weeks and compounded tirzepatide at $199 every 4 weeks. The 12-month plans on that page are $99 a month and $149 a month, paid up front as $1,188 and $1,788. The 4-week figures are the pair, and they match the catalog rows checked 26 October 2026. The gap on the 4-week bill is $50. Enhance.MD's 1-month cards are $249 every 4 weeks for core semaglutide and $329 every 4 weeks for advanced tirzepatide, each with $50 off the first order. The gap on the card price is $80. Those card prices match the catalog recurring figures checked 26 October 2026. The page also prints longer plans at $237, $224, and $212 a month for semaglutide and $313, $296, and $280 a month for tirzepatide. Those are different commitments.

Found's cash prices are per 28-day cycle, and the page says the cycle covers clinical care, the medication, and the membership. Semaglutide is $179 the first cycle, then $289. Tirzepatide is $219 the first cycle, then $359. The later-cycle gap is $70. Those later figures match the catalog, checked 25 October 2026. A 28-day cycle is not a calendar month, and the annualized monthly equivalent is not the charge the page asks for.

CoreAge's paid-in-full prices, and Lttl's starting prices

CoreAge Rx prints $79 a month for semaglutide and $129 a month for tirzepatide and says the prices shown are starting at, based on a 12-month plan paid in full. The page does not print the lump sum. The catalog, checked 25 October 2026, stores the same monthly equivalents. There is no separate calendar-month continuing price on the page that was opened, so $79 and $129 are the pair, and they are not month-to-month prices. The gap is $50.

Lttl's semaglutide page says starting at $89 a month. The tirzepatide page says starting at $139 a month. A banner on both pages says up to $140 off the first month and that a code is auto-applied. This note does not print the code and does not subtract $140, because the banner does not say the starting price is the price after that amount. The catalog rows for these two Lttl pages have no stored dollar, checked 21 October 2026 for semaglutide and 25 October 2026 for tirzepatide. The starting prices are what the pages printed on 26 October 2026. The gap between those starting figures is $50.

Embody's homepage cards and the one-month product pages

Embody's one-month semaglutide page prints a sale price of $79 and a regular price of $299. The one-month tirzepatide page prints a sale price of $129 and a regular price of $349. The regular-price gap is $50, and the sale-price gap is $50. The pages do not say the sale is limited to the first month. Those sale and regular pairs are the catalog figures, checked 24 October 2026, and the product pages still print them.

The homepage, opened the same day, prints two different cards: weekly GLP-1 injections at a flat $69 a month, and weekly GLP-1/GIP injections at a flat $119 a month. The cards do not say semaglutide, and they do not say tirzepatide. The gap between the cards is $50. This note does not treat $69 as the semaglutide sale price or $119 as the tirzepatide sale price. They are homepage cards. The named drug prices remain the product-page pairs.

Brand prices from NovoCare, and from partner pages

NovoCare's Wegovy home-delivery page separates the pill from the pen. Self-pay for the pill is $149 a month at 1.5 mg, $199 a month at 4 mg, and $299 a month at 9 mg and 25 mg. One month of tablets is 1 bottle of 30 tablets. For the pen, patients new to the Wegovy savings offer or to NovoCare home delivery pay $199 for each month of 0.25 mg and 0.5 mg. That offer is for 2 monthly fills through 31 December 2026. After that, the page lists $349 a month for Wegovy 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, or 2.4 mg, and $399 a month for Wegovy HD injection 7.2 mg. One month of the pen is 1 box of 4 pens.

NovoCare's Ozempic home-delivery page uses the same shape for the pen. Patients new to the offer or to NovoCare home delivery pay $199 for each month of 0.25 mg and 0.5 mg, for 2 monthly fills through 31 December 2026, then $349 a month for 0.25 mg, 0.5 mg, or 1 mg, and $499 a month for 2 mg. One month is 1 box of 1 pen. The page header also shows tablet dollar amounts. The footnote that defines a bottle of 30 tablets does not map those dollars to named Ozempic doses, so this note does not assign them.

LillyDirect's Zepbound page returned a security check on 26 October 2026 and no vial price. This note does not repeat an older LillyDirect dollar. Partner pages that were readable are a different source. Eden lists Wegovy at $1,695 a month and Zepbound at $1,399 a month. On that pair the tirzepatide brand is the lower price, which is the reverse of the compounded pairs above. Gala lists Ozempic from $1,299 a month cash. Sesame lists Wegovy pen without insurance at $199 a month for the first two months for new Wegovy patients, then $349 a month. Sesame lists Zepbound KwikPen without insurance at $299 a month for 2.5 mg, $398 for 5 mg, $499 for 7.5 mg, and $698 for 10 mg, 12.5 mg, and 15 mg. The catalog's Zepbound comparison figure for Sesame is the $299 price, checked 25 October 2026. The higher strengths are on the page and are not that single comparison figure.

A NovoCare self-pay offer is the manufacturer's home-delivery price for that brand. It is not a compounded price, and it is not Eden's or Sesame's price.

The compounded pair is not the brand pair

FDA's page, content current as of 1 October 2026, says compounded drugs are not FDA approved and that the agency does not review them for safety, effectiveness, or quality before they are marketed. yourEra, Strut, Sprout, Enhance.MD, and Embody say in their own words that the compounded product is not FDA approved. A $40 or $100 gap between two compounded prices is a billing fact. It is not a statement that the lower price is the same drug as Wegovy, Ozempic, or Zepbound.

The single-drug cost notes keep the full continuing ranges, the prepaid columns, and the pharmacy names. This page is only the pair: the same provider, the same day, semaglutide beside tirzepatide. Where the provider prints both, the compounded tirzepatide figure is higher. Eden's brand pair runs the other way. Until a LillyDirect vial page can be read, the official tirzepatide self-pay ladder is not in this note.